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International journal of interdisciplinary dentistry

versión impresa ISSN 2452-5596versión On-line ISSN 2452-5588

Resumen

LEON, Víctor; O’RYAN, Juan Alberto; NOGUERA, Alfredo  y  SOLE, Pedro. Mesenchymal stem cells as a treatment for the regeneration of degenerative articular diseases. A narrative review. Int. j interdiscip. dent. [online]. 2021, vol.14, n.3, pp.253-256. ISSN 2452-5596.  http://dx.doi.org/10.4067/S2452-55882021000300253.

Introduction:

To date, temporomandibular joint (TMJ) reconstruction remains a clinical challenge, and its treatment has focused mainly on pain relief and the eventual restoration of joint function.

Aim:

To describe, through a narrative review, the properties and characteristics of different mesenchymal cells for the regenerative treatment of joint diseases.

Material and method:

An electronic search of the literature was carried out in the databases of PubMed, EBSCO, Web of Science, Scopus and The Cochrane Library since the year 2005, in English and Spanish, emphasizing joint regeneration of the knee and the TMJ. Studies where joint degeneration was the result of trauma were excluded. Eighteen articles were evaluated.

Results and discussion:

The reported literature highlights the different protocols used with mesenchymal stem cells derived from bone marrow, adipose tissue and human umbilical cord, with results of joint regeneration in all cases at radiographic and histological level when possible. The treatment of joint diseases in the TMJ has been poorly described, with good results in case reports and observational studies. Because of this, it is important to continue investigating this matter to establish clear treatment protocols in the temporomandibular joint.

Palabras clave : Stem cells; Temporomandibular joint; Regeneration.

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