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Revista chilena de cardiología

On-line version ISSN 0718-8560

Abstract

HAMEAU, René et al. Coronary artery disease in patients infected with HIV. Rev Chil Cardiol [online]. 2021, vol.40, n.2, pp.139-147. ISSN 0718-8560.  http://dx.doi.org/10.4067/S0718-85602021000200139.

Cardiovascular diseases, particularly coronary artery disease are relevant in patients with the human immunodeficiency virus (HIV). For several years accelerated atheromatosis, a cause of increased prevalence in coronary disease, has been recognized in these patients. However, the pathophysiological mechanisms involved are multiple and complex, including viral factors, the inflammatory and immune response triggered by the virus, traditional cardiovascular risk factors, and the effects of combined antiretroviral therapy. This review of the literature addresses these mechanisms and updates the main clinical studies that support them. Cardiovascular risk assessment and guidelines for revascularization of HIV patients with CHD are also discussed.

Keywords : HIV; Coronary artery disease; Review.

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