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Revista chilena de cardiología

versión On-line ISSN 0718-8560

Resumen

ROMAN, Domingo; SOLAR, Carlos  y  PIZARRO, Isabel. TRACE ELEMENTS IN CARDIOVASCULAR TISSUES OF PATIENTS UNDERGOING CARDIAC SURGERY IN A HEAVY METAL CONTAMINATED AREA, THE ANTOFAGASTA REGION (CHILE). Rev Chil Cardiol [online]. 2013, vol.32, n.3, pp.214-220. ISSN 0718-8560.  http://dx.doi.org/10.4067/S0718-85602013000300005.

The Antofagasta population is exposed to environmental contamination with heavy metals (HM). Trace elements (TE) might interact with As either as agonists or antagonists. The total concentracions of V, Cr, Mn, Co, Ni, Cu, Se and B in the right atrium (RA), left internal mammary artery (LIMA), saphenous vein (SV) and adipose tissue (AT) from patients undergoing cardiac surgery are reported. Methods: LIMA, SV, RA and AT from 50 patients with myocardial infarction submitted to revascularization surgery in Antofagasta (exposed group, E) or Santiago (non exposed group NE, 20 patients) were analyzed. Optical and atomic techniques were used for analysis of HM and TE. Results: Significant inter elemental correlations were observed for B in group E, (p<0.05), which are not present in group NE. The RA concentrarion of B in group A ranged from 24.72 to 932.03 ug/g, substancially higher than concentracion of the other elements under study. Corresponding concentra-rions of B in the NE group were 25.21 to 56. 87 ug/g. Conclusion: B was the most enriched element in the exposed group, followed by As and Mn. Cu content was significantly lower in RA and LIMA from patients in the non exposed group.

Palabras clave : Environmental contamination; heavy metals; trace elements; cardiovascular tissues.

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