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Revista chilena de cirugía

On-line version ISSN 0718-4026


BARRERA E, ALEJANDRO; BANNURA C, GUILLERMO; GUERRA C, JUAN F  and  SALVADO B, JOSÉ A. Surgical rectal biopsy for the diagnosis of diseases caused by abnormal protein deposits. Rev Chil Cir [online]. 2006, vol.58, n.6, pp.447-450. ISSN 0718-4026.

Background: Rectal biopsy is used for the diagnosis of amyloidosis and more recently for the diagnosis of hyaline inclusion diseases. Aim: To report the experience with surgical rectal biopsies for the diagnosis of diseases caused by deposit of abnormal proteins. Material and methods: Retrospective review of nine patients (age range 4-67 years, five females) subjected to a surgical rectal biopsy. Results: The indication for the biopsy was the suspicion of systemic amyloidosis in four patients and hyaline inclusion disease in five. The biopsy was obtained under regional or general anaesthesia, that allowed an optimal anal dilatation, obtaining adequate surgical pieces with good haemostasis. The diagnosis was confirmed in three patients with suspected amyloidosis and in three patients with suspected hyaline inclusion disease. Conclusions: Surgical rectal biopsy is useful for the diagnosis of amyloidosis or hyaline inclusion disease and must be performed in the surgical room

Keywords : Rectal biopsy; amyloidosis; hyaline inclusion disease.

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