SciELO - Scientific Electronic Library Online

 
vol.65 número4EXPERIMENTAL INVESTIGATION AND MECHANISM ANALYSIS: EFFECT OF CONCENTRATION AND TEMPERATURE ON THE VISCOSITY OF NOVEL MWCNT-MUSTARD OIL NANOFLUIDREMOVAL OF REACTIVE RED 198 FROM AQUEOUS SOLUTIONS USING MODIFIED CLAY: OPTIMIZATION, KINETIC AND ISOTHERM índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados

Revista

Articulo

Indicadores

Links relacionados

  • En proceso de indezaciónCitado por Google
  • No hay articulos similaresSimilares en SciELO
  • En proceso de indezaciónSimilares en Google

Compartir


Journal of the Chilean Chemical Society

versión On-line ISSN 0717-9707

Resumen

BRAVO-ARREPOL, Gastón et al. CHEMICAL CHARACTERIZATION OF LIGNANS FROM Araucaria araucana A NATIVE CONIFER OF CHILE AND EVALUATION OF THEIR CYTOTOXICITY AND ANTIOXIDANT ACTIVITIES. J. Chil. Chem. Soc. [online]. 2020, vol.65, n.4, pp.4953-4957. ISSN 0717-9707.  http://dx.doi.org/10.4067/S0717-97072020000404953.

Araucaria araucana is a native conifer of Chile commonly called Araucaria. The knots of Araucaria are extremely hard wood and highly rot-resistant, they can be found in the forest decades after that the tree has dead and decomposed. Here we report the phytochemical characterization of different parts of the Araucaria as stemwood, branch and knots, founding a remarkable difference in the content of extractables in these parts, as well as the lignan composition, which is higher in knots than in branches or stemwood. Eudesmin was isolated and crystallized from organic extract of knots, its structure was determinate by NMR; moreover, secoisolariciresinol, lariciresinol and matairesinol were identified by GCMS and HPLC in contrast to standards, and quantified in stemwood, branch and knots. The results showed that secoisolariciresinol is the main lignan with 45.77 mg g−1, followed by eudesmin with 22.68 mg g−1, lariciresinol 4.57 mg g−1 and matairesinol with 1.19 mg g−1. The antioxidant activity in terms of DPPH assay showed that knotwood extract displays the higher activity, meanwhile that eudesmin did not displays activity in DPPH assay. The cytotoxic activity against SHSY5Y neuroblastoma and P3X myeloma cell lines, revelated a moderate activity of extracts, while eudesmin did not showed activity.

Palabras clave : Araucaria araucana; lignan; eudesmin; DPPH activity; cytotoxic activity.

        · texto en Inglés     · Inglés ( pdf )