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Journal of the Chilean Chemical Society

versión On-line ISSN 0717-9707

Resumen

URZUA, ALEJANDRO; OLGUIN, ANGEL  y  SANTANDER, ROCÍO. ARISTOLOCHIC ACIDS IN THE ROOTS OF ARISTOLOCHIA CHILENSIS, A DANGEROUS CHILEAN MEDICINAL PLANT. J. Chil. Chem. Soc. [online]. 2013, vol.58, n.4, pp.2089-2091. ISSN 0717-9707.  http://dx.doi.org/10.4067/S0717-97072013000400041.

The chemical composition of aristolochic acids (AAs) from the roots of A. chilensis was determined by high-performance liquid chromatography with diode-array detection (HPLC-DAD), a technique widely used for the detection and quantification of AAs in herbal medicines. The roots contained a mixture of AA-I (1), AA-II (2), AA-III (3), AA-IV (4), AA-Ia (5), AA-IIIa (6), AA-IVa (7), and aristoloside (8), indicating that A. chilensis is not suitable for use as a medicinal plant due to the harmful effects of the aristolochic acids.

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