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vol.54 número2ANTHOCYANINS THAT CONFER CHARACTERISTIC COLOR TO RED COPIHUE FLOWERS (LAPAGERIA ROSEA)IMPROVEMENT OF GALANGIN SOLUBILITY USING NATIVE AND DERIVATIVE CYCLODEXTRINS: AN UV-Vis AND NMR STUDY índice de autoresíndice de assuntospesquisa de artigos
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Journal of the Chilean Chemical Society

versão On-line ISSN 0717-9707

Resumo

CHENG, MING-JEN et al. SECONDARY METABOLITES FROM THE CULTURE BROTH OF ACTINOMYCETE ACROCARPOSPORA SP. FIRDI 001 AND THEIR ANTIMICROBIAL ACTIVITY. J. Chil. Chem. Soc. [online]. 2009, vol.54, n.2, pp.198-200. ISSN 0717-9707.  http://dx.doi.org/10.4067/S0717-97072009000200024.

Two natural new compounds, pyrroline-2-one (1) and 2-(2-amino-3-methyl-butyrylamino)-3-(4-hydroxy-phenyl)-propionic acid (2), together with nine known compounds, iodinin (3), thymine (4), V-(2-hydroxy-phenyl)-acetamide (5), (Z)-pulchellalactam (6), uracil (7), nicotinic acid (8), nicotiamide (9); p-nitrophenol (10) and indole 3-carboxylic acid (11), all were isolated from the EtOAc extract of the culture broth of anew actinomycete Acrocarpospora sp. strain, FIRDI 001. The structures were elucidated by ID and 2D NMR spectroscopy and mass spectrometry. Furthermore, the isolated compounds were subjected to evaluate the antimicrobial activity. Compounds 2, 3 and 10 showed antimicrobial activity. The active metabolite, iodinin existed as a major metabolite in this study.

Palavras-chave : Acrocarpospora sp; Actinomycetes; Secondary metabolites; alkaloids; Iodinin; Antimicrobial activity.

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