Resumo

MORALES, GLAUCO et al. SECONDARY METABOLITES FROM FOUR MEDICINAL PLANTS FROM NORTHERN CHILE: ANTIMICROBIAL ACTIVITY AND BIOTOXICITY AGAINST Artemia salina. J. Chil. Chem. Soc. [online]. 2003, vol.48, n.2, pp.13-18. ISSN 0717-9707.  http://dx.doi.org/10.4067/S0717-97072003000200002.

Antibacterial activity and biotoxicity against Artemia salina of chloroform and alcohol extracts and isolated products from four plants used in ethnomedicine in northern Chile is reported. Nine compounds already identified were isolated from aerial parts of Artemisia copa Phil., Acantholippia punensis Botta, Ephedra andina Poepp. ex C. A . Mey and Haplopappus rigidus Phil : 3,5 ­ dihydroxy ­ 6, 7, 3', 4' ­ tetramethoxyflavone, lupeol, b ­ amyrine , b ­ sitosterol, ephedrine, 2 ­ ethylhexanol phthalate , 18 ­ acetoxy ­ cis ­ cleroda ­ 3,13 Z ­ dien ­ 15 ­ oic acid, 5,4' ­ dihydroxy ­7­ methoxyflavanone and 3,5,7 ­ trihydroxy ­ 6, 4' ­ dimethoxyflavone

Palavras-chave : Artemisia copa Phil.(copa-copa); Acantholippia punensis Botta. (rica ­ rica); Ephedra andina Poepp.ex C. A . Mey (pingo ­ pingo); Haplopappus rigidus Phil. (baylahuen); medicinal plants; flavonoids; terpenoids; antimicrobial activity.