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International Journal of Morphology

versão On-line ISSN 0717-9502

Resumo

FARUK, E. R; DEVECI, E; KALKANLI, S  e  DEVECI, B. The Effects of Nicotine on the Incisive Teeth and Expression of Vimentin in Rats. Int. J. Morphol. [online]. 2013, vol.31, n.2, pp.516-519. ISSN 0717-9502.  http://dx.doi.org/10.4067/S0717-95022013000200026.

Nicotine is an alkaloid toxic effects of oral cavity. In this study,14 adult Sprague-Dawley rats weighing 230-260 mg (±10 mg) were used as experimental animal. The rats of experimental group (n=6) were nicotinized systemically with nicotine sulphate, 2mg/kg subcutaneously, daily in period of 28 days. Pulp, alveolar bone tissue, periodontal membrane and gingival epithelial junction were investigated in these regions in incisive teeth longitudinal cross-section. Thinning of the collagen fibers in the pulp tissue, vascular congestion, and inflammatory cell infiltration were observed. Mesenchymal tissues that is stained positive for vimentin lay underneath the epithelium. A strong expression of vimentin can be observed in formed periodontal ligament.

Palavras-chave : Nicotine; Rat; Vimentin.

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