SciELO - Scientific Electronic Library Online

 
vol.29 issue4Studies on Tongue of Reptilian Species Psammophis sibilans, Tarentola annularis and Crocodylus niloticusImmunohistochemical Fiber Type Profile in the Human Vocal Muscle author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

Share


International Journal of Morphology

On-line version ISSN 0717-9502

Abstract

BOZZO, Aída Andrea et al. Chronic Stress Effects on Adrenal Cortex Cellular Proliferation in Pregnant Rats. Int. J. Morphol. [online]. 2011, vol.29, n.4, pp.1148-1157. ISSN 0717-9502.  http://dx.doi.org/10.4067/S0717-95022011000400013.

Chronic stress by immobilization during pregnancy may cause alterations in mechanisms maintaining homeostasis in the adrenal gland. The objective of this study was to quantify cellular proliferation index in the adrenal cortex during pregnancy second half and assess the effects of chronic stress on it. Adrenal cortex proliferation index in stressed rats showed a significant decrease at 12 and 17 days of gestation, while at day 21 it did not show differences with the control treatments. Moreover, proliferation index of reticular zones in control and experimental rats, exhibited a significant reduction in comparison to glomerular and fascicular zones of adrenal cortex during the three gestation days studied. In conclusion, chronic stress by immobilization produces a decrease in cellular proliferation index at 12 and 17 gestation days, which may be related to changes in plasmatic concentrations of corticosterone and prolactin and, to the reduction of specific growth factors. Furthermore, the observed proliferation diminishment in reticular zone regarding the other cortical zones would be consistent with the migration theory of adrenal cells.

Keywords : Chronic stress; Cellular proliferation; Adrenal cortex; Pregnancy.

        · abstract in Spanish     · text in English     · English ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License