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International Journal of Morphology

On-line version ISSN 0717-9502

Abstract

UEMA, Rogério Takeyoshi; FAZAN, Valéria Paula Sassoli; CHERRI, Jesualdo  and  PICCINATO, Carlos Eli. Bovine Peritoneum Protection Role on Intestinal Adhesions to a Vascular Graft: A Morphological Analysis. Int. J. Morphol. [online]. 2008, vol.26, n.2, pp.269-274. ISSN 0717-9502.  http://dx.doi.org/10.4067/S0717-95022008000200004.

The present study aimed to experimentally evaluate the protection role of glycerin preserved bovine peritoneum (BP) against intestinal adhesions to a vascular graft. Experiments were performed on 24 adult rabbits, randomly dived into two groups. All animals were submitted to a vascular graft over the infra-renal aorta and vena cava. Group 1(12 animals ) was submitted to a BP patch on the retroperitoneal opening, between the vascular prosthetic graft and the intestinal loops. Group II (12 animals ) had the retroperitoneal opening sutured. After 7, 14, 28 and 60 days, 3 animals of each group were randomly killed and the retro peritoneum, with or without the BPpatch, was removed for histological analysis. The histological analysis showed that the BP stimulated a moderate to intense inflammatory reaction at the beginning of the experiments and on the 60-day evaluation, the inflammatory reaction was mild, limited to the BP border with its histological structure preserved. In conclusión, the BP is a safe and cheap interposition material to be used between vascular grafts and intestinal loops, presenting a protection role against adhesions between them.

Keywords : Bovine peritoneum; Morphology; Aortoenteric fistula; Vascular graft.

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