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Revista chilena de radiología

versión On-line ISSN 0717-9308


CORDOVEZ M, Jorge et al. Use of lesion volumes and loads for monitoring patients with multiple sclerosis: Local experience and literature review. Rev. chil. radiol. [online]. 2013, vol.19, n.4, pp.156-164. ISSN 0717-9308.

Multiple sclerosis (MS) is a common demyelinating disease that involves the central nervous system causing focal lesions in the brain and spinal cord causing diverse neurological development deficits, many of them severe and irreversible, affecting and invaliding a large percentage of young productive-aged patients. MRI exams have improved diagnostic capability compared to computed tomography, but in this decade the development of new magnets, coils and software have allowed the development of quantitative neuroradiology which achieves the evaluation of parameters such as total brain volume, of each of its structures, as well as semi-automated or automated counting of the lesion load, allowing better monitoring of each individual patient in relation to a particular event such as a new neurological deficit in an outbreak of the disease, a previously undetected cognitive impairment or in related to a given treatment. We will show our local experience using the FreeSurfer software in our habitual practice, as well as other post-processing software, this being the first experience of its use in multiple sclerosis published in our country.

Palabras clave : Brain volume; FreeSurfer; Lession load; Magnetic resonance imaging; MIPAV software; Multiple sclerosis.

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