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Revista chilena de radiología

versión On-line ISSN 0717-9308


URBINA R, Jesús et al. Relative pressure measurement in thoracic aorta and pulmonary artery in healthy volunteers and patients with Tetralogy of Fallot repaired by 4D Flow cardiovascular MRI . Rev. chil. radiol. [online]. 2012, vol.18, n.4, pp.157-162. ISSN 0717-9308.

Objective. To validate the utility of 4D Blood Flow and Navier-Stokes equations to create relative pressure (RP) maps in the aorta and pulmonary artery (PA) in healthy volunteers and patients with repaired tetralogy of Fallot (TOF). Methods. A 4D flow sequence of whole heart and its major vessels was acquired in 10 healthy volunteers and 6 patients with repaired TOF. The root of the ascending aorta was used as the reference point to calculate RP along five different points of this area. In addition, relative pressure of both right and left PA was measured as correlated to absolute pressure. Results. Patients with repaired TOF showed greater pulmonary artery (PA) relative pressure differences between maximum and minimum values when compared to volunteers (p <0.05). Additionally, aortic relative pressures had an excellent correlation with published data, whether using 4D flow or by catheterization. Conclusions. 4D Flow MRI may represent a new non-invasive and non operator-dependent diagnostic tool in CV disease management.

Palabras clave : 4D Flow; Congenital heart defects; Magnetic resonance imaging; Relative pressure difference; 4D flow.

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