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Revista chilena de neuro-psiquiatría

On-line version ISSN 0717-9227


PEREA, María Victoria; GARCIA, Ricardo; CANAS, Manuel  and  LADERA, Valentina. Information processing speed in Alzheimer's disease. Rev. chil. neuro-psiquiatr. [online]. 2019, vol.57, n.3, pp.228-237. ISSN 0717-9227.


Slowdown of information processing speed (ISP) is a common finding in a variety of brain pathologies. From a clinical point of view, assessment of ISP is of great interest since cognitive processing can be affected and, consequently, show consequences on daily living activities. The aim was to study the time in performing different executive tasks, as measures of information processing speed, in subjects with different severity of Alzheimer's Disease. Number of mistakes in the different taks has also been analysed.


50 patients with Alzheimer's Disease presenting mild (n = 17), moderate (n = 17) and moderately severe (n = 16) cognitive impairment, according to Global Deterioration Scale; and 60 subjects with no cognitive impairment. Trail-Making test, Zoo Map test and Stroop test were administered.


Statistically significant differences were found between all groups in all measures performed, time of performance and number of mistakes in Trail-Making test; time of performance and number of mistakes in the Zoo Map test; and words, color and, word-color conditions in Stroop test (p < 0,01).


Our results suggest that information processing in patients with Alzheimer's Disease is slower compared to patients with no cognitive impairment, since a higher time of performance and rate of mistakes are presented.

Keywords : Alzheimer's Disease; Assessment; Slowdown; Information processing.

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