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Revista chilena de neuro-psiquiatría

On-line version ISSN 0717-9227


VALDIVIESO-JIMENEZ, Glauco. Clinical severity in bipolar disorder and borderline personality disorder and its comorbidity. Rev. chil. neuro-psiquiatr. [online]. 2019, vol.57, n.2, pp.107-117. ISSN 0717-9227.


Bipolar disorder and borderline personality disorder are diagnoses that have a wide variety of symptoms, however, it is described that the comorbidity of both intensifies the clinical severity as the appearance of a greater number of suicide attempts or self-harm. The objective of the study was to determine and compare the sociodemographic characteristics, clinical severity and symptoms in patients within these 3 groups.


The type of study was descriptive and qualitative, observational and transversal design. A sample of 92 clinical records of patients treated at the National Hospital Víctor Larco Herrera during the periods of January 2010 to May 2018 was used. Sociodemographic variables (age, sex, marital status, religion, level of education and occupation) and clinical severity (number of hospitalizations, suicide attempts, refusal of medication, response to treatment, substance abuse, current hospitalization and severity symptoms) using a data collection form.


The sociodemographic variables with statistical significance and higher frequency were female sex (p = 0.049), single marital status (p = 0.003), catholic religion (p = 0.009), as well as the variables of clinical severity with statistical significance were the number of hospitalizations (p = 0.015), psychotic symptoms (p = 0.009), irritability (p = 0.038), impairment (p = 0.000) and number of symptoms of severity (p = 0.030) in TB, BPD and their comorbidity.


The clinical severity is associated with the number of hospitalizations, the presence of psychotic symptoms, irritability, dysfunctionality and the number of severe symptoms in patients with only TB diagnosis, BPD and their comorbidity.

Keywords : Bipolar disorder; borderline personality disorder; comorbidity; severity (source: MeSH).

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