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Revista chilena de neuro-psiquiatría

On-line version ISSN 0717-9227


MARTINEZ-AGUAYO, Juan Carlos; ARANCIBIA M, Marcelo  and  SILVA I, Hernán. Suicide psychopharmacology: a critical analysis. Rev. chil. neuro-psiquiatr. [online]. 2015, vol.53, n.2, pp.127-133. ISSN 0717-9227.

Suicide is an important worldwide death cause. Although 90% or more of those who commit suicide suffer from a psychiatric disorder, an isolated pathology does not fully explain the complex phenomenon of suicide. Because of the multifactorial behavior suicidal pattern, biological, psychological and social factors are implicated. Given the above, a single pharmacological management of the underlying disease or some symptoms such as anxiety and impulsivity, should not be enough to address or prevent suicidal behavior in its entirety. Because of the complexity and the interrelationship of risk factors for suicide, it is very unlikely that a single medication controls all the aspects involved; thereby it is difficult to ascribe the actual antisuicidal effect of a particular drug with certainty. However, the current literature despite its limitations supports an antisuicidal effect of particular drugs such as lithium and clozapine.

Keywords : Suicide; psychopharmacology; prevention.

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