Resumen

MENDEZ-HERRERA, Carlos R. The subthalamic nucleus in the pathophysiology of Parkinson's disease and its role as a surgical target. Rev. chil. neuro-psiquiatr. [online]. 2011, vol.49, n.1, pp.62-68. ISSN 0717-9227.  http://dx.doi.org/10.4067/S0717-92272011000100008.

Parkinson's disease is one of the most common causes of neurological disability, it caused by selective loss of neurons at the substantia nigra, which causes an imbalance in the functioning of the basal ganglia. In the pathophysiological events underlying this disease, hyperactivity of the subthalamic nucleus is more often associated with major clinical manifestations; this structure also plays a fundamental role in motor control, making it an excellent surgical target.

Palabras clave : Parkinson's disease; subthalamic nucleus; basal ganglia.

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