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Revista chilena de neuro-psiquiatría

versión On-line ISSN 0717-9227

Resumen

SANCHEZ Z, Víctor; GUERRERO T, Rodrigo; VERDUGO L, Renato  y  CARTIER R, Luis. Recurrent Acute Ophthalmoplegia without ataxia. Rev. chil. neuro-psiquiatr. [online]. 2010, vol.48, n.2, pp.147-151. ISSN 0717-9227.  http://dx.doi.org/10.4067/S0717-92272010000300007.

They may exhibit increased anti-GQ1b antibodies in Miller Fisher syndrome, Guillain-Barre syndrome with ophthalmoplegia, Bickerstaff Rhombencephalitis, and Acute Ophthalmoplegia without ataxia , the so called “anti-GQ1b syndromes”. We report a 72 years old man who was admitted because of diplopia, acute onset ophthalmoplegia and retro-ocular pain. He had a similar episode five years ago, fully recovered. At admission he showed complete bilateral ophthalmoplegia without ptosis, miosis and slight enophthalmos of the right eye. Preserved muscle strength, deep tendon areflexia, without sensory or cerebellar commitment. CSF and electromyography were normal. Brain MRI showed uptake and T2 hyperintensity of the third and sixth cranial nerves. Spinal cord MRI showed no change in the spinal roots. Serum anti-GQ1b increase of 46.2 / 25. He improved without treatment. Thirty days later, paresis was only the sixth pair. The anti-GQ1b is a marker that identifies neuropathies with oculomotor commitment. The acute ophthalmoplegia without ataxia have normal reflex, 30% had areflexia. There are only Guillain-Barré and Miller-Fisher syndromes recurrent case reports with anti-GQ1b. It would be the first case of recurrent anti-GQ1b-positive acute ophthalmoplegia without ataxia.

Palabras clave : Acute ophthalmoplegia without ataxia; anti-QQ1b antibodies; Anti-GQ1b recurrent syndromes.

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