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Revista chilena de obstetricia y ginecología

versión On-line ISSN 0717-7526

Resumen

MENDOZA TASCON, Luis Alfonso et al. Determinantes biológicos de mortalidad neonatal, en una población de mujeres adolescentes y adultas de un hospital en Colombia. Rev. chil. obstet. ginecol. [online]. 2017, vol.82, n.4, pp.424-437. ISSN 0717-7526.  http://dx.doi.org/10.4067/s0717-75262017000400424.

Introduction.

Neonatal death is associated with maternal, obstetric, fetal, neonatal, and health determinants.

Objective.

To establish the determinants associated with neonatal mortality in a Colombian intensive care unit.

Methods.

Case-control study nested in a cohort, where 5567 live infants were included, of which 125 died. Stata 11.0® descriptive statistics were constructed and associations were established using odds ratio (95% confidence interval). Logistic regression was used in the multivariate analysis. A value of p <0.05 was considered significant.

Results.

Mortality occurred in 2.25% of neonates, with 76.80% of deaths occurring between 0-7 days. Maternal and obstetric determinants independently associated with neonatal mortality included numbers of visits in prenatal control less than 6, spontaneous preterm labor, third trimester bleeding, and chronic hypertension. Among neonatal determinants, the need for cardiorespiratory resuscitation, prematurity or low birth weight, severe bacterial infections, hyaline membrane disease, pulmonary hypertension, congenital malformations and chromosomal abnormalities, and hypertrophic cardiomyopathy were independently associated with neonatal mortality. For complications and adverse events, there was an independent and statistically significant association for infections associated with health care, intravenous haemorrhage degrees III and IV of Papille, and pulmonary hemorrhage.

Conclusions.

Neonatal mortality is due to maternal, obstetric and fetal-neonatal determinants, so improving neonatal care will reduce neonatal mortality.

Palabras clave : Neonatal mortality; Gestation; Maternal determinants; Obstetric determinants; Neonatal determinant.

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