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Revista chilena de obstetricia y ginecología
versión On-line ISSN 0717-7526
Resumen
CAMPOVERDE V, Priscila et al. PTI y embarazo: Una experiencia con Rituximab. Rev. chil. obstet. ginecol. [online]. 2017, vol.82, n.1, pp.80-83. ISSN 0717-7526. http://dx.doi.org/10.4067/S0717-75262017000100012.
Idiopathic thrombocytopenic purpura ( ITP) is a condition associated with each 500-1000 pregnancies . Its early recognition and proper management during pregnancy, can reduce both maternal and fetal morbidity and mortality. Corticosteroids as first-line treatment for ITP in pregnant women is the same as in the general population, with responses observed between the 5th and 7th day, approximately 50-60 % of patients respond favorably. The case presented is a pregnant patient in the 2th trimester with refractory ITP treatment with corticosteroids, very low levels of platelets and high risk of bleeding so the use of Rituximab is decided, a monoclonal antibody (category C FDA) with little prescription in pregnancy. We describe our experience in this case.
Palabras clave : Rituximab; Pregnancy; thrombocytopenia.