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Revista chilena de obstetricia y ginecología

versão On-line ISSN 0717-7526

Resumo

CASTILLO TAUCHER, Silvia; FUENTES SOTO, Ana María; PAULOS MILLANAO, Alejandro  e  DE LA ROSA REBAZA, Eduardo. Estudio cromosómico en abortos espontáneos. Rev. chil. obstet. ginecol. [online]. 2014, vol.79, n.1, pp.40-46. ISSN 0717-7526.  http://dx.doi.org/10.4067/S0717-75262014000100007.

Approximately 15% of all clinical pregnancies end in spontaneous abortion. The most common cause of spontaneous abortion is a fetal chromosomal abnormality, such as an autosomal trisomy, monosomy X and polyploidy. From May 1991 until February 2013 we performed 2,416 cytogenetic studies in abortion tissues in the Cytogenetics Unit of the Clinical Laboratory Clínica Alemana de Santiago. We want to share information about the distribution of the findings in these studies, and want to disseminate the strategy we have implemented since February 2010 with multiple probes study of fluorescence in situ hybridization (FISH) in cases where the tissue culture had not progressed, allowing to provide some important information regarding the presence or absence of certain chromosomal abnormalities in all studies.

Palavras-chave : Spontaneous abortion; cytogenetics; aneuploidy; FISH.

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