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Revista chilena de obstetricia y ginecología
On-line version ISSN 0717-7526
Abstract
JIMENEZ COTES, Evert et al. Preeclampsia: la evolución diagnóstica desde la genómica y la proteómica. Rev. chil. obstet. ginecol. [online]. 2013, vol.78, n.2, pp.148-153. ISSN 0717-7526. http://dx.doi.org/10.4067/S0717-75262013000200014.
Preeclampsia was defined as the presence of hypertension evidenced two blood pressure readings ≥ 140/90 (systolic blood pressure ≥ 140 mmHg or diastolic ≥ 90 mmHg) and proteinuria greater than 0.3 g/day after the twentieth week pregnancy in previously normotensive patients. Still the real cause is unknown, although there are some theories that suggest that a combination of environmental factors, genetic and immunological may increase susceptibility. Genomics and proteomics have been providing necessary progress in the understanding and diagnosis of new biomarkers that point to novel advances in the diagnosis, prevention and treatment of this disease.
Keywords : Preeclampsia; genomics; proteomics.