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Revista chilena de obstetricia y ginecología

On-line version ISSN 0717-7526


DE LA CALLE FM, María et al. Embarazo con acromegalia materna asociada a crecimiento intrauterino fetal retardado. Rev. chil. obstet. ginecol. [online]. 2011, vol.76, n.3, pp.183-187. ISSN 0717-7526.

Pregnancy in acromegalic patients is an infrequent event, due to perturbed gonadotroph function. On the other hand, pregnancy may cause an enlargement of the adenoma or an increase of growth hormone (GH) secretion. We report the case of a pregnant acromegalic woman who had been previously operated by transphenoidal approach and treated with cabergolin. A progressive decrease of insuline-like growth factor-1 (IGF1) level during pregnancy without tumoral syndrome or visual troubles was shown during pregnancy. Neither metabolic complication nor hypertension were detected. Ultrasound performed at 31th week showed a decrease of the fetal growth. At 37th week, an intrauterine growth restriction and oligohydramnios was diagnosed. It was performed a cesarean section and it was delivered a healthy 2700 grams male newborn. Our report suggests that pregnancy could not influence negatively in acromegalic patient but may be associated with intrauterine growth restriction.

Keywords : Acromegaly; pregnancy; intrauterine growth restriction.

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