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vol.68 issue5INFECCION POR VIRUS PAPILOMA HUMANO PERSISTENTE Y NEOPLASIA CERVICOUTERINABIOPSIA QUIRURGICA CON MARCACION PREOPERATORIA EN LESIONES NO PALPABLES DE LA MAMA: EXPERIENCIA DE 10 AÑOS author indexsubject indexarticles search
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Revista chilena de obstetricia y ginecología

Print version ISSN 0048-766XOn-line version ISSN 0717-7526

Abstract

CUELLO F, Mauricio et al. TUMOR DE CELULAS DE LA GRANULOSA DEL OVARIO. Rev. chil. obstet. ginecol. [online]. 2003, vol.68, n.5, pp.376-386. ISSN 0048-766X.  http://dx.doi.org/10.4067/S0717-75262003000500004.

We report 10 patients with granulosa cell tumor of the ovary diagnosed and/or treated at our institution between 1991 and 2002. A review of the clinical presentation, the surgical approach, the utility of frozen-section biopsy, the histology and the stage of the disease, treatment modalities, and follow-up is done. Eighty percent of the patients were stage I. Four out of five patients whose frozen-section biopsies were done, the diagnosis was confirmed at the definitive report. At early stage, surgery was the main modality of treatment (unilateral salpingo-ophorectomy in patients who wanted to preserve fertility and bilateral salpingo-ophorectomy plus total abdominal hysterectomy who did not). Young patients who were diagnosed after initial surgery underwent complete surgical staging. The median follow-up was 38 months (range 12 to 140 months). Only one recurrence was diagnosed, at the periaortic lymph nodes, and treated with hormone therapy plus chemotherapy. We conclude that the granulosa cell tumor is an uncommon entity with different clinical presentations and with good prognosis when diagnosed at early stage (stage I) and treated with surgery alone

Keywords : Granulosa cell tumour; surgery; chemotherapy; ovarian cancer.

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