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Revista chilena de nutrición

 ISSN 0717-7518

SANTOS, Silvia; VINDEROLA, Gabriel; SANTOS, Luama    ARAUJO, Edilene. Bioavailability of chelated and non-chelated minerals: a systematic review. []. , 45, 4, pp.381-392. ISSN 0717-7518.  http://dx.doi.org/10.4067/S0717-75182018000500381.

Minerals are essential elements for life and their balance is important for multiple physiological, biochemical and metabolic processes. The way they are ingested determines their functionality. It has been suggested that chelated minerals have better bioavailability. The objective of this work was to perform a systematic review of published articles to verify if chelated minerals are more bioavailable than non-chelated minerals. Publications were reviewed in the period between 2007 and 2017 in Pubmed, Lilacs and Cochrane Library databases in Portuguese and English with the keywords: “mineral chelates”, “micronutrient chelate”, “bioavailability micronutrient chelate”, organic mineral, “iron chelate”, “zinc chelate”, “magnesium chelate”, “copper chelate” and “chelate” and their respective translations in Portuguese (the original language of this article). 446 articles were selected and 24 papers were left after the application of inclusion / exclusion criteria. Of these, 15 were in animals (manganese, zinc, copper, iron, chromium, cobalt and selenium) and 9 in humans, and focused on iron and calcium. The studies showed greater absorption, transport and bioavailability for chelated compared to non-chelated minerals. More human studies, however, are necessary to address the bioavailability of other minerals, as well as the standardization of the dosajes of these micronutrients.

: Absorption; Bioavailability; Chelate; Copper; Iron; Micronutrients; Organic mineral; Zinc.

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