Resumen

FARIAS N, María Magdalena  y  KLAASSEN L, Julieta. NEW LIPID EMULSIONS ENRICHED WITH OMEGA-3: IS THERE A REAL BENEFIT ON PARENTERAL NUTRITION?. Rev. chil. nutr. [online]. 2011, vol.38, n.1, pp.77-83. ISSN 0717-7518.  http://dx.doi.org/10.4067/S0717-75182011000100009.

Total parenteral nutrition allows nutritional supports for patients who are not able to receive oral intake or enteral nutrition. Fatty acids are administrated as lipid emulsions and a lower inflammatory cytokine level has been described after administration of Omega-3. This could be a benefit for critical patients by a potential antiinflamatory and immunomodulation effect. Also, for patients with respiratory distress syndrome, the lower cytokine effect may directly affect pulmonary vessels by vasodilatation and consequently improve respiratory function. Different studies have shown positive clinical outcomes after Omega-3 administration, while other studies have failed to demonstrate significant results. Mechanisms involved with this possible immunomodulation by fish oil are well known, although further research is necessary to clarify the clinical relevance of these mechanisms.

Palabras clave : polyunsaturatedfatty acid omega-3; fish oil; lipid emulsion; perenteral nutrition; immunomodulation.

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