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Revista chilena de nutrición

versión On-line ISSN 0717-7518

Resumen

MIRANDA C, Daisy; LEIVA B, Laura; LEON S, José Pablo  y  DE LA MAZA C, Ma Pía. DIAGNOSIS AND TREATMENT OF VITAMIN D DEFICIENCY. Rev. chil. nutr. [online]. 2009, vol.36, n.3, pp.269-277. ISSN 0717-7518.  http://dx.doi.org/10.4067/S0717-75182009000300009.

Nutritional status of vitamin D has regained importance in the last few years because its deficiency is highly prevalent, and because, apart from its well known effects on bone metabolism, this vitamin participates in cellular proliferation and differentiation and muscle strength and balance, among other effects. The active molecule is 1,25(OH)2D, but serum concentration of total 25 OH vitamin D (i.e. including ergocalciferol or vitamin D2 plus chole calciferol or vitamin D3) is the preferred indicator of vitamin D status. Recent evidences suggest the need to increase dietary recommendations in adults up to 1,000 IU/day. However, in deficiency states it is often necessary to supplement with pharmaceutical preparations, which contain higher doses of this vitamin since the amounts previously employed were not able to return levels to normal. In the present article we present the entire list of vitamin D preparations commercially available in Chile. The difficulty of choosing the most adequate product for an individual patient becomes clear, because there are only few formulations containing more than 800IU and, in addition they are usually combined with calcium, biphosphonates or multiple minerals and other vitamins.

Palabras clave : 1 ,25(OH)2D; cholecalciferol; ergocalciferol; deficiency; 250HD.

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