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vol.16 issue2CORRELATION BETWEEN CORTICAL SURFACES AND THEIR ASYMMETRIES IN POSTMORTEM HUMAN BRAINSEFFECT OF AGE ON THE VOLUME AND WEIGHT OF HUMAN TESTIS author indexsubject indexarticles search
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Revista chilena de anatomía

Print version ISSN 0716-9868

Abstract

MENDES, Glória E. F. et al. EFFECTS OF LOW-DOSE EXPOSURE OF RAT FETUSES PANCREAS TO METHYLMERCURY.: MORPHOMETRIC AND STEREOLOGIC STUDIES. Rev. chil. anat. [online]. 1998, vol.16, n.2, pp.177-183. ISSN 0716-9868.  http://dx.doi.org/10.4067/S0716-98681998000200002.

Methylmercury chloride (20 mg/kg body weight), when administered orally to Wistar rats on day 10 of pregnancy, originated smaller fetuses and placentas. Death and resorptions were present and no gross malformations were seen. Histologically, the larger pancreatic acini of treated fetus showed irregular shape with larger pyknotic nuclei. The nuclei varied in size and shape. The lumen was small. In the faintly eosinophilic cytoplasm of the cells less numerous secretory granules were present. The ducts were disorganized and presented larger nuclei. The pancreatic islets were immature and less organized. The data were analyzed with morphometric and stereologic techniques.

Keywords : Methylmercury; Rat; Fetus; Pancreas; Morphometry; Stereology.

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