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Revista chilena de infectología

versión impresa ISSN 0716-1018

Resumen

TASAYCO-MAGALLANES, Emilio et al. Evaluation of two brands of test of ELISA for the diagnosis of HTLV-1 against Peruvian samples. Rev. chil. infectol. [online]. 2020, vol.37, n.6, pp.780-783. ISSN 0716-1018.  http://dx.doi.org/10.4067/S0716-10182020000600780.

As Peru is endemic to HTLV-1, it is important to know the reliability of the most used screening trademarks in our country. In the present study, we evaluated two brands of ELISA (Biokit and Wantai) for the detection of antibodies against HTLV-1/2 against Peruvian samples. Both brands were evaluated against 242 sera: 123 positive for HTLV-1 and 119 negative for HTLV-1 (Reference: Immunoblot). We estimated diagnostic accuracy parameters. The sensitivity, specificity, PPV, NPV and validity index of Biokit were: 100%, 93.2%, 93.8%, 100%, 96.6%; respectively and Wantai were 99.1% for all parameters. We conclude that the Biokit brand is the most suitable for use in the National Reference Laboratory of Sexually Transmitted Viruses HIV/AIDS, Peru.

Palabras clave : HTLV-1; ELISA; Biokit; Wantai.

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