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Revista chilena de infectología

Print version ISSN 0716-1018

Abstract

BAY, Constanza et al. Nasal phaeohyphomycosis by Curvularia spicifera in pediatric patient with neutropenia and acute myeloid leukemia. Rev. chil. infectol. [online]. 2017, vol.34, n.3, pp.280-286. ISSN 0716-1018.  http://dx.doi.org/10.4067/S0716-10182017000300014.

There are very few reports of pediatric patients with infections by dematiaceous filamentous fungi. In this publication we report a case of invasive fungal infection of the nasal septum by Curvularia spicifera in a pediatric patient with acute myeloid leukemia. The patient presented with a painful scabby wound in the nasal vestibule. Culture and universal PCR were consistent with Curvularia spicifera. Early management with surgical debridement and bi-associated antifungal therapy achieved complete resolution of the lesions, with no evidence of dissemination and relapses. Clinical management of these fungal infections represents a challenge as the antifungal selection and duration of therapy is not yet well stablished.

Keywords : Phaeohyphomycosis; mycoses; sinusitis; Curvularia spicifera; Bipolaris spicifera.

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