SciELO - Scientific Electronic Library Online

 
vol.28 issue5Diagnosis and treatment of opportunistic infections in HIV/AIDS adult patientsAcute gastroenteritis caused by a Vibrio cholerae non-O1, non-O139 strain harboring a genetic region homologous to the VpaI-7 pathogenicity island author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

Share


Revista chilena de infectología

Print version ISSN 0716-1018

Abstract

AFANI S, Alejandro  and  GALLARDO O, Ana M. Antiretroviral resistance in human immunodeficiency virus infection. Rev. chil. infectol. [online]. 2011, vol.28, n.5, pp.461-469. ISSN 0716-1018.  http://dx.doi.org/10.4067/S0716-10182011000600011.

Resistance to anti-retroviral therapy is one of the main problems in the favorable outcome of treatment in HIV patients, as well as toxicity and adherence to treatment. Resistance has increased in recent years, and it is evaluated through genotyping and phenotypic tests. Information provided by these studies is crucial when deciding the most appropriate treatment. However, genotype interpretation is complex and subject to frequent change, because of the incorporation of new drugs and the appearance of new resistance patterns. This review aims ,understanding the fundamental concepts of antiretroviral resistance (ARV), which examines the general principles, mechanisms and patterns of resistance, both for the traditional family of anti-retrovirals, as well as for the most recently licensed drugs.

Keywords : drug resistance; antiretroviral therapy; mutation.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License