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Revista chilena de infectología

versión impresa ISSN 0716-1018


DIAZ J., M. CRISTINA; JULIET L., CHRYSTAL; MONZON DE LA T, ARACELI  y  RODRIGUEZ-TUDELA, JUAN LUIS. Surgical site abscess by Scedosporium prolificans: first report in Chile and review. Rev. chil. infectol. [online]. 2004, vol.21, n.1, pp.65-69. ISSN 0716-1018.

The aim of this article is to report the first case of infection by Scedosporium prolificans in our country. The patient corresponds to a 27 year-old man with chronic renal failure, hypertension, submitted to a renal transplant, in treatment with cyclosporine, azathioprine and prednisone. Twenty five days after the transplant, he noticed a fluctuating increase of volume under the surgical wound. In three consecutive purulent exudates and in tissue obtained at surgery, Scedosporium prolificans was isolated as an only agent. The histopathological study revealed structures compatible with septate hyphae. The patient was treated by surgical debridement, Amphotericin B and Itraconazol obtaining a complete cicatrization of the wound. S prolificans is a hyaline filamentous fungi, resistant to Amphotericin B and azoles, considered currently an emerging pathogen. It is responsible of localized infections associated to surgery and/or trauma, as well as fatal disseminated infections in immunocompromised hosts, specially oncological, in presence of neutropenia, and transplants. It is important to consider this microorganism in the differential diagnosis of emerging fungal infections

Palabras clave : Scedosporium prolificans; surgery.

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