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Revista chilena de pediatría

versión impresa ISSN 0370-4106

Resumen

RUBILAR O, Lilian et al. Chronic pulmonary aspergillosis associated to multiple airway papillomatosis: Case-report and literature review. Rev. chil. pediatr. [online]. 2006, vol.77, n.4, pp.382-387. ISSN 0370-4106.  http://dx.doi.org/10.4067/S0370-41062006000400007.

Aspergillosis is rare in children, although Aspergillus species cause a wide spectrum of diseases. The host immune system is a major determinant in the development of particular forms of aspergillosis, such as acute invasive pulmonary aspergillosis, allergic bronchopulmonary aspergillosis, aspergilloma and chronic pulmonary aspergillosis (CPA). Objective: Present experience in the management of CPA in a patient with pulmonary papillomatosis. Case: 8 years-old girl with pulmonary papillomatosis, treated with laser surgery and topic Mitomicin at different periods, without complete resolution. She presents frequent pulmonary infectious exacerbations; in the last one Aspergillus fumigatus was isolated in 6 cultures. The chest X-ray and tomography show multiple pulmonary cavities in the right upper lobe, leading to the diagnosis of CPA. The patient received therapy with Itraconazol, achieving clinical-radiological success and negative cultures. Conclusions: CPA is rare in children, however, it is necessary an early diagnosis in order to establish the adequate therapy that avoids pulmonary fibrosis and respiratory insufficiency

Palabras clave : Aspergillus; chronic pulmonary aspergillosis; pulmonary papillomatosis; Itraconazol.

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