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Revista chilena de pediatría

versión impresa ISSN 0370-4106


VOGEL S, Andrea; AZOCAR P, Marta; NAZAL CH, Vilma  y  SALAS DEL C, Paulina. Treatment guidelines for the idiopathic nephrotic syndrome in children, Recommendations of the Pediatric Nephrology Branch of the Chilean Pediatric Society. Rev. chil. pediatr. [online]. 2006, vol.77, n.3, pp.295-303. ISSN 0370-4106.

The idiopathic nephrotic syndrome (INS) in children is a benign clinical entity, because in most cases it corresponds to Minimal Change Disease, showing an intact renal function after a long period of time. Some few cases correspond to other glomerulopathies, especially Focal Segmental Glomerulo Sclerosis, with higher risk of renal failure. Although INS has a high rate of response to steroids, more than 60% of cases present numerous relapses, bringing together various complications due to the nephrotic condition itself and the prolonged use of steroids. In these patients, along with those who present steroid-resistance, other therapeutic schemes need to be applied, sometimes with important side effects. The aim of this update is to teach INS treatment based on an extended literature research; nevertheless, it is important not to forget that each patient must have its individual prescription according to risks and benefits of the therapy

Palabras clave : idiopathic nephrotic syndrome; minimal change; focal segmental glomerulo sclerosis; steroids; cyclosporine; therapy; children.

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