SciELO - Scientific Electronic Library Online

 
vol.149 número11Características clínicas de pacientes ingresados por COVID-19 en un Hospital de alta complejidad de la región de la Araucanía-ChileEfecto de una intervención no farmacológica multidimensional en un grupo de personas con deterioro cognitivo leve índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados

Revista

Articulo

Indicadores

Links relacionados

  • En proceso de indezaciónCitado por Google
  • No hay articulos similaresSimilares en SciELO
  • En proceso de indezaciónSimilares en Google

Compartir


Revista médica de Chile

versión impresa ISSN 0034-9887

Resumen

HUIDOBRO E., Juan Pablo; VEGA, Jorge; SEPULVEDA, Rodrigo A.  y  ASTORGA, Andrés. Comparative performance of urinary creatinine excretion estimating equations. Rev. méd. Chile [online]. 2021, vol.149, n.11, pp.1561-1568. ISSN 0034-9887.  http://dx.doi.org/10.4067/S0034-98872021001101561.

Background:

24-hour urine collection accuracy is generally evaluated based on the values of urine creatinine (UCr) excretion, usually using ranges adjusted by weight. UCr excretion depends on several factors. Equations to estimate UCr in 24-hour collection (UCr/24h) that consider these factors have been developed. However, these formulas have not been evaluated in a sample of Latinamerican origin.

Aim:

To evaluate the performance of the existing UCr/24 h estimation equations in a sample of Latinamerican origin.

Material and Methods:

24-hour urine collections from 181 ambulatory patients were analyzed. Measured UCr/24h was compared with estimated UCr (eUCr) through the equations of Ix (CKD-EPI), Gerber-Mann, Goldwasser, Cockcroft-Gault, Rule, Walser, Kawasaki, Tanaka and Huidobro. Performance of the nine equations to estimate UCr/24h was evaluated with the Pearson correlation and Lin concordance coefficients, and Bland-Altman method. Bias, precision, and accuracy (percentage of collections within 30% of measured UCr or P30) were also calculated.

Results:

Measured UCr/24h in the 181 patients was 1236 + 378 mg. Correlation coefficient (Pearson) of the eUCr/24h with the equations of Walser, Ix and Huidobro and the measured UCr/24h was strongly positive. Rule and Kawasaki equations had the lowest positive correlation coefficients. Bias was similar using the formulas of Walser, Goldwasser, Kawasaki, Ix and Huidobro. Walser, Ix, Huidobro, Cockcroft-Gault and Goldwasser equations had good accuracy (P30 > 85%), while Gerber-Mann, Tanaka, Rule and Kawasaki formulas had a P30 < 65%.

Conclusions:

Walser, Ix and Huidobro equations had the best performance to estimate UCr/24h excretion in a population of latinamerican origin.

Palabras clave : Creatinine; Glomerular Filtration Rate; Kidney Function Tests; Renal Elimination.

        · texto en Español     · Español ( pdf )