SciELO - Scientific Electronic Library Online

 
vol.149 issue3Personal and familial features associated with organ donation in Chilean adultsAn update on parathyroid carcinoma author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google

Share


Revista médica de Chile

Print version ISSN 0034-9887

Abstract

HORTA, Gloria; SOTO, Sebastián  and  LABARCA, Gonzalo. Vitamin D levels in patients with inflammatory bowel disease. Rev. méd. Chile [online]. 2021, vol.149, n.3, pp.393-398. ISSN 0034-9887.  http://dx.doi.org/10.4067/s0034-98872021000300393.

Background:

Inflammatory Bowell Diseases (IBD), either ulcerative colitis (UC) or Chron's disease (CD) are commonly associated with intestinal malabsorption, and insufficient levels 1-25 hydroxycholecalciferol (vitamin D). These insufficient levels could be linked with an increased risk of clinical disease activity.

Aim:

To report vitamin D levels in patients with IBD living in Southern Chile and their possible association with clinical disease activity.

Material and Methods:

A prospective, observational study in outpatients with IBD living in Los Angeles, Chile. Demographic data and clinical activity using clinical scores were recorded. Vitamin D levels and fecal calprotectin were measured.

Results:

We studied 44 patients, 32 (73%) with UC and 12 (27%) with CD. The median age at diagnosis was 33 years old. Forty-one (93%) had mild-inactive disease and 3 (7%) a moderate disease. Mean vitamin D levels were 15.2 ± 7.1 ng/ml. Twenty five percent of patients had sufficient levels (> 20 ng/ml), 35% insufficient levels and 40% poor levels. No association between these levels and disease activity was found.

Conclusions:

These patients with IBD had a high frequency of hypovitaminosis D.

Keywords : Inflammatory Bowel Diseases; Vitamin D; Vitamin D Deficiency.

        · text in Spanish     · Spanish ( pdf )