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Revista médica de Chile

versión impresa ISSN 0034-9887


MARTINEZ, María Pía  y  GALLARDO, Ismael. Reliability and construct validity of SF-12 to measure health related quality of life in Chilean subjects. Rev. méd. Chile [online]. 2020, vol.148, n.11, pp.1568-1576. ISSN 0034-9887.


Health-Related Quality of Life (HRQoL) is understood as a multidimensional variable, mostly measured using the SF-12 questionnaire. However, this measurement doesn't always replicate the factorial structure theoretically expected, hindering potential conclusions.


To assess the reliability and validity of SF-12 questionnaire in a representative sample of Chilean participants.

Material and Methods:

Information was obtained from the National Quality of Life Survey performed in Chile during 2015-16. During the survey, SF-12 was answered by 7041 participants older than 15 years, with a median age of 47 years (63% women).


SF-12 has reliability, but it does not have construct validity. The analysis suggests that there is a factorial structure that resembles theory, only when factors and items are related.


The practical importance of these results highlight the need to measure HRQoL using more extensive scales.

Palabras clave : Quality of Life; Reproducibility of Results.

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