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Revista médica de Chile

Print version ISSN 0034-9887


MARTORELL, Miquel et al. Association of menopause with cardiovascular risk. Analysis of data from the 2016-17 Chilean national health survey. Rev. méd. Chile [online]. 2020, vol.148, n.2, pp.178-186. ISSN 0034-9887.


Menopause exposes women to an increased cardiovascular risk.


To determine the association between menopause and cardiovascular risk factors in Chilean adult women using data from the National Health Survey (NHS) 2016-2017.

Material and Methods:

Data from 2,139 women over 40 years of age participating in the NHS 2016-2017, with information about menopause and cardiovascular risk factors was used. Expansion factors were applied to this sample, obtaining an expanded sample of 3,733,191 participants. Laboratory values (blood glucose, triglycerides, HDL and total cholesterol) and anthropometric measurements (body weight, height and waist circumference) were analyzed. The presence of hypertension, diabetes, and metabolic syndrome (MetS) were also recorded.


Sixty seven percent of surveyed women were menopausal and had higher systolic blood pressure than non-menopausal participants. Menopause was significantly associated with hypertension (Odds ratio (OR): 2.43 [95% confidence intervals (CI): 1.71; 3.45], p < 0.01) and diabetes (OR: 2.05 [95% CI: 1.32; 3.19], p < 0.01). However, no association was observed with obesity, abdominal obesity or MetS.


In these women, a positive association was identified between menopause and hypertension as well as diabetes.

Keywords : Cardiovascular Diseases; Diabetes Mellitus; Hypertension; Menopause; Obesity.

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