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Revista médica de Chile

Print version ISSN 0034-9887

Abstract

HUIDOBRO E., Juan Pablo; TAGLE, Rodrigo  and  GUZMAN, Ana María. Estimation of glomerular filtration rate with creatinine. Rev. méd. Chile [online]. 2018, vol.146, n.3, pp.344-350. ISSN 0034-9887.  http://dx.doi.org/10.4067/s0034-98872018000300344.

Glomerular filtration rate (GFR) is the best approximation to global renal function and its estimation is of great relevance for clinical practice. Since the measurement of GFR by reference methods is complex, costly and not widely available, its routine evaluation is performed using endogenous biomarkers. Within these, creatinine is the most commonly used. It allows the estimation of GFR by means of its clearance or by formulas based on its concentration on plasma. Creatinine measurement should be performed using enzimatic methods as they confer more accurate values than Jaffe methods, especially for normal and low creatinine levels.

Keywords : Creatinine; Glomerular Filtration Rate; Kidney Function Tests.

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