Abstract

SARMIENTO, Mauricio et al. Autologous hematopoietic cell transplantation in patients with multiple myeloma. Experience in 53 patients. Rev. méd. Chile [online]. 2014, vol.142, n.12, pp.1497-1501. ISSN 0034-9887.  http://dx.doi.org/10.4067/S0034-98872014001200001.

Background: Autologous hematopoietic cell transplantation (THA) in patients with multiple myeloma and amyloidosis is the standard of care to promote disease free survival and quality of life. Aim: To report our experience with THA in patients with multiple myeloma. Material and Methods: Retrospective review of the hematopoietic cell transplantation database of a hospital of a Medical School. Forty seven patients with multiple myeloma and six with amyloid light chain amyloidosis were identified. Clinical and demographic data were obtained from the records. Results: The overall five year survival of patients was 55%. Transplant-related or non-relapse mortality occurred in 7%. We found no differences in outcomes among patients younger or older than 50 years. Conclusions: Our data supports that THA can be done in our country with similar results to those obtained in international transplantation centers. Chronological age should not be a limitation to offer this therapy to patients with multiple myeloma and amyloidosis.

Keywords : Amyloidosis; Hematopoietic stem cell transplantation; Multiple myeloma.

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