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Revista médica de Chile

Print version ISSN 0034-9887

Abstract

ARNAIZ, Pilar et al. Association of carotid intima media thickness with blood pressure and HDL cholesterol in children. Rev. méd. Chile [online]. 2012, vol.140, n.10, pp.1268-1275. ISSN 0034-9887.  http://dx.doi.org/10.4067/S0034-98872012001000005.

Background: Cardiovascular risk factors must be controlled since childhood. Aim: To assess the association of carotid intima media thickness (CIMT) with the components of the metabolic syndrome in Children. Material and Methods: Cross sectional assessment of 299 children aged 11.5 ± 0.9years (58% women) with and without metabolic syndrome components. Anthropometric parameters and blood pressure were measured and a blood sample was obtained to measure blood glucose and lipids. CIMT was measured using high resolution ultrasound. Results: Ninety three percent of children were post puberal, 64% were overweight and 25% had metabolic syndrome. Mean and maximum CIMT correlated with systolic blood pressure (r = 0.21 and 0.21 respectively p < 0.01). Children with a CIMTover the 75th percentile had higher blood pressure and lower HDL cholesterol. A stepwise logistic regression accepted both variables as predictors of CIMT with odds ratios for mean CIMT of 1.46 (1.19-1-79) and 0.81 (0.7-0.94) perfive units of change, respectively. Conclusions: In this group of children systolic blood pressure and HDL cholesterol are associated to CIMT.

Keywords : Blood pressure; Carotid Intima-Media thickness; Child; Cholesterol HDL.

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