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Revista médica de Chile

Print version ISSN 0034-9887

Abstract

CORTES, Víctor et al. The contribution of Goldstein and Brown to the study of cholesterol metabolism. Rev. méd. Chile [online]. 2012, vol.140, n.8, pp.1053-1059. ISSN 0034-9887.  http://dx.doi.org/10.4067/S0034-98872012000800014.

Background: In December 1985, the Nobel Prize of Medicine was awarded to Drs. Joseph L. Goldstein and Michael S. Brown for their fundamental scientific work on the regulation of cholesterol metabolism mediated by the low density lipoprotein receptor pathway. This article briefly reviews the academic and research accomplishments of Drs. Brown and Goldstein as a tribute to these physician-scientists for their well-deserved award and enormous contribution to biomedical science worldwide.

Keywords : Cholesterol; Nobel prize; Receptors; lipoprotein.

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