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Revista médica de Chile

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MIRANDA C, Marcelo; TORRES T, Juan Pablo; LARRANAGA L, Carmen  and  ACUNA L, Guillermo. Meningomyelitis associated with infection by human herpes virus 7: Report of two cases. Rev. méd. Chile [online]. 2011, vol.139, n.12, pp.1588-1591. ISSN 0034-9887.

Human herpesvirus 7 (HHV-7) may cause encephalomyelitis in immune competent adults. We report two patients infected by the virus. A 34-year-old male presenting with paraparesis and a sensitive deficiency located in D6 dermatome. Cerebrospinal fluid had 35 white blood cells per mm3 and 75 mg protein per dl. A PCR-microarray examination was positive for HHV-7. The patient was treated with prednisolone and ganciclovir with full recovery. A 27-year-old male presenting with headache, fever and diarrhea. Cerebrospinal fluid analysis showed 160 cells per mm3 and 75 mg protein per dl. Viral RNA detection was positive for HHV-7. The patient was managed with analgesia and rest and was discharged with the diagnosis of viral meningitis. Our communication supports the notion that HHV-7 may be considered as pathogen factor in humans, even in immune competent ones.

Keywords : Encephalomyelitis; Herpesvirus 7, human; Meningitis, viral.

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