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Revista médica de Chile

versão impressa ISSN 0034-9887

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PILLEUX C, LILIAN; MARTINEZ G, ALEJANDRA; DONOSO S, MARIO  e  CARRASCO L, CRISTIAN. Immune thrombocytopenic purpura associated to hepatitis C virus infection: Report of one case. Rev. méd. Chile [online]. 2010, vol.138, n.9, pp.1140-1143. ISSN 0034-9887.  http://dx.doi.org/10.4067/S0034-98872010000900009.

Hepatitis C Virus (HCV) is a cause of secondary chronic immune thrombocytopenic purpura (ITP). We report a 43 year old man with mild Hemophilia A, who received blood transfusions during childhood, that consulted for epistaxis and ecchymoses. The laboratory showed a platelet count of 23.000/mm3, positive HCV serology and elevated transaminases. Steroids administered in pulses followed by oral doses resulted in a partial response requiring a second pulse and association of azathioprine. A steroidal diabetes appeared. Given his refractoriness, splenectomy and liver biopsy were performed. He continued on azathioprine maintaining a platelet count near 50.000/mm3 but continued with bleeding episodes. Liver biopsy showed a chronic active hepatitis.

Palavras-chave : Hepatitis C, chronic; Purpura, thrombocytopenic; Splenectomy.

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