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Revista médica de Chile

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WHITTLE, CAROLINA; HEPP, JUAN; ARMAS, RODOLFO  and  SCHULTZ, MARCELA. Porphyria cutanea tarda, hemosiderosis and hepatocellular carcinoma: Report of one case. Rev. méd. Chile [online]. 2010, vol.138, n.5, pp.581-585. ISSN 0034-9887.

Porphyria cutanea tarda (PCT) is a hereditary or acquired disease. It can be unleashed by iron overload, alcohol, estrogens and other conditions. In these patients, hepatic involvement can be associated to cirrhosis, iron overload or C and B viral infections, that are predisposing factors for hepatocellular carcinoma. We report a 69-year-old man with PTC, hemosiderosis and hepatocarcinoma. The tumor was diagnosed during a routine ultrasound examination for early detection of malignant lesions. The patient was subjected to a right hepatic excision. The pathological examination of the surgical piece confrmed the diagnosis and disclosed free surgical margins. After 18 months of follow up, the patient had a relapse and a liver transplantation was performed.

Keywords : Carcinoma; Hepatic; Hepatocellular; Hemosidrosia; Porphyrias.

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