SciELO - Scientific Electronic Library Online

vol.138 número4Cuerpos extraños en la vía aérea: Uno a cada lado en forma simultánea. Caso clínicoEnteroplastía transversa seriada como alternativa en el tratamiento del síndrome de intestino corto: Caso clínico índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados




Links relacionados


Revista médica de Chile

versión impresa ISSN 0034-9887


FERNANDEZ-REY, CRISTINA LIDIA et al. Sarcoidosis presenting as partial seizures: Report of one case. Rev. méd. Chile [online]. 2010, vol.138, n.4, pp.473-477. ISSN 0034-9887.

The nervous system is affected in 10% of patients with sarcoidosis. However, neurological disturbances are rarely the frst manifestation of the disease. We report a 36-year-old woman presenting with partial seizures that generalized secondarily. Magnetic resonance showed a left parietal cortical-subcortical lesion with a minimal mass effect, moderate vasogenic edema and intense enhancement with intravenous contrast. A magnetic resonance spectroscopy disclosed a low aggressiveness profle, compatible with an infammatory lesion. Angiotensin converting enzyme levels were normal. The lesion was excised and the pathological study showed the presence of granulomas with dubious necrosis. The patient was treated with antituberculous drugs. One year later, the lesion had grown and a thorax CT scan showed numerous mediastinal and hilar lymphadenopathies. A new determination of angiotensin converting enzyme disclosed elevated levels and the biopsy of mediastinal lymph nodes confrmed the presence of sarcoidosis.

Palabras clave : Peptidyl-dipeptidase A; Sarcoidosis; Seizures.

        · texto en Español     · Español ( pdf )


Creative Commons License Todo el contenido de esta revista, excepto dónde está identificado, está bajo una Licencia Creative Commons