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Revista médica de Chile

Print version ISSN 0034-9887


BAHAMONDES B, Carlos  and  GODOY O, Jorge. Cyclosporine-induced gingival hyperplasia: Report of one case. Rev. méd. Chile [online]. 2007, vol.135, n.3, pp.370-374. ISSN 0034-9887.

Gingival enlargement can be an adverse effect of ciclosporine A and nifedipine use. It has a high relapse rate if the drugs are not discontinued. There is a genetic predisposition to the development of this condition and dental biofilm can also play a role. We report a 64 years old male who received a renal allograft and was treated with cyclosporine and nifedipine. He required six surgical interventions for generalized gingival enlargement. After the sixth relapse, the patient was subjected to a periodontal treatment to eliminate the dental biofilm, which decreased the rate of recurrence of gingival enlargement

Keywords : Biofilm; Cyclosporine; Gingival hyperplasia.

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