SciELO - Scientific Electronic Library Online

 
vol.132 número3Tratamiento crónico combinado con iloprost y sildenafil en un paciente con hipertensión pulmonar primariaCosto-efectividad de la promoción de la salud en Chile: Experiencia del programa «¡Mírame!» índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados

Revista

Articulo

Indicadores

Links relacionados

Compartir


Revista médica de Chile

versión impresa ISSN 0034-9887

Resumen

MELLADO T, Patricio et al. Intra-arterial thrombolysis in locked-in syndrome: Report of two cases. Rev. méd. Chile [online]. 2004, vol.132, n.3, pp.357-360. ISSN 0034-9887.  http://dx.doi.org/10.4067/S0034-98872004000300012.

Locked-in syndrome is a dramatic clinical condition, the patient is awake, can listen and breath, but is unable to move any muscle, conserving only the vertical eye movements. The most common cause of locked-in syndrome is the thrombosis of the basilar artery and commonly leads to death, frequently due to pneumonia. Intravenous and intra arterial thrombolysis have been used successfully in a selective group of patients with ischemic stroke. There is only one report of two patients with locked-in syndrome who were treated successfully with intra arterial thrombolysis. Other authors, based in their experiences, do not recommend this treatment. We report two female patients aged 63 and 26 years, with Locked-in syndrome due to a basilar thrombosis who were treated successfully with intra arterial thrombolysis using ecombinant tissue plasminogen activator (r-TPA). The lapses between the onset of the symptoms and thrombolysis were 5 and 8 hours respectively. A complete recanalization was obtained in both patients during the thrombolysis. One year after, the first patient has only a moderate ataxia, walking with assistance and the other has a normal neurological examination (Rev Méd Chile 2004; 132: 357-60 ).

Palabras clave : Locked-in syndrome; Plasminogen activators; Thrombolytic therapy; Vertebrobasilar insufficiency.

        · texto en Español     · Español ( pdf )

 

Creative Commons License Todo el contenido de esta revista, excepto dónde está identificado, está bajo una Licencia Creative Commons