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Revista médica de Chile

Print version ISSN 0034-9887

Abstract

CAMPUSANO M, Claudia  and  LOPEZ M, José Manuel. Complete recovery of life-threatening hungry bone syndrome using long-term ambulatory intravenous calcium infusion: Report of one case. Rev. méd. Chile [online]. 2003, vol.131, n.7, pp.779-784. ISSN 0034-9887.  http://dx.doi.org/10.4067/S0034-98872003000700010.

We report a 29 years old woman with a highly symptomatic primary hyperparathyroidism. After parathyroid adenoma excision, she presented a prolonged and life threatening hypocalcemia, due to a severe hungry bone syndrome. Conventional treatment with oral and intravenous calcium and calcitriol supplementation failed to raise serum and urinary calcium or to relief symptoms. After one month, we indicated a continuous intravenous calcium infusion allowing, during 6 months, an adequate outpatient management. Initial T scores for bone density were markedly low (L2-L4: -3.14; femoral neck: -3.07) and they increased 17% after 18 days of calcium infusion. After 147 days of treatment bone density was normal, increasing by 61%. The present case shows that the hungry bone syndrome can be a real risk for patients and a complex therapeutic challenge. With an appropriate calcium supply an early, fast and complete recovery of bone mass can be achieved (Rev Méd Chile 2003; 131: 779-84)

Keywords : Calcitriol; Calcium metabolism disorders; Hyperparathyroidism; Hypocalcemia.

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