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Revista médica de Chile

versión impresa ISSN 0034-9887

Resumen

PRIETO D, Juan Carlos  y  GRUPO DE ESTUDIO MULTICENTRICO DEL INFARTO et al. Changes in pharmacotherapy for acute myocardial infarction: Comparison of two periods. Rev. méd. Chile [online]. 2001, vol.129, n.5, pp.481-488. ISSN 0034-9887.  http://dx.doi.org/10.4067/S0034-98872001000500002.

Background: Pharmacotherapy of Chilean patients with acute myocardial infarction has been recorded in 37 hospitals since 1993. Aim: to compare pharmacotherapy for acute myocardial infarction in the period 1993 to 1995 with the period 1997-1998. Patients and methods: Drug prescription during hospital stay was recorded in 2957 patients admitted to Chilean hospitals with an acute myocardial infarction in the period 1993-1995 and compared with that of 1981 subjects admitted in the period 1997-1998. Results: When compared with the former period, in the lapse 1997-1998 there was an increase in the frequency of prescription of aspirin (93 and 96.1% respectively) ß blockers (37 and 55.2% respectively) and angiotensin converting enzyme inhibitors (32 and 53%). The prescription of thrombolytic therapy did not change (33 and 33.7% respectively). There was a reduction in the prescription of calcium antagonists and antiarrhythmic drugs. Conclusions: During the period 1997-1998, the prescription of drugs with a potential to reduce the mortality of acute myocardial infarction, increased. The diffusion of guidelines for the management of this disease may have influenced this change. (Rev Med Chile 2001; 129: 481-8)

Palabras clave : Adrenergic beta-antagonists; Aspirin; Myocardial infarction; Thrombolytic therapy.

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